Kraurosis and leukoplakia vulva

Kraurosis and leukoplakia vulva - clinical concepts. Vulvar cancer on the background of these diseases occur in 20-50 % of cases. Kraurosis and leukoplakia vulva occurs more often in women in the period of pre-and postmenopausal women . Causes and pathogenesis of these diseases is not entirely clear , but many researchers have noted in these patients gipoestrogeniya and / or exchange- endocrine disorders (diabetes ) .

Vulvar kraurosis - atrophy of the stratified squamous epithelium ( from the Greek craurosis - dry, wrinkled ) .

Leukoplakia vulva characterized by proliferation ( hyperplasia ) of the squamous epithelium , a violation of its differentiation and maturation .

The main complaint of patients with leukoplakia and kraurosis vulva - painful thrust itching , worse at night, when overheating and exertion. Itching often lasts for years and lead to neuropsychiatric disorders , disability and sometimes suicidal thoughts .

Mucocutaneous covers the vulva at kraurosis thinner , they are brilliant , dry, depigmented , easily vulnerable to resemble parchment .

Clinically with dry patches of leukoplakia note whitish or yellowish , located in restricted areas or apply to the entire vulva . Often seen scratching the vulva , sometimes associated infection ( pronounced hyperemia and edema).

Diagnosis and examination of patients with leukoplakia and kraurosis vulva begin with a detailed examination vulvoskopiey ( use a colposcope ) . All patients showed some sugar in the blood, cytology prints or surface scrapings from ulcer sites. In cases of doubt, or when the results of cytology testifying cell atypia , tissue biopsy is necessary followed by histological examination . Place determined by biopsy vulvoskopii .

Treatment kraurosis and leukoplakia vulva. Leukoplakia and kraurosis vulva are intractable diseases. One of the most effective and promising treatments now considered low-intensity laser radiation. Already after 4-5 sessions of laser therapy improves the health of patients , pruritus weakens. Subsequently, skin and mucous membrane become normal properties . In the absence of the possibility of laser therapy for the treatment of kraurosis vulva thoroughly recommend hygiene vulva, lacto-vegetarian diet , sedatives ( valerian , etc.) , antihistamines ( diphenhydramine, suprastin , tavegil etc.) , hormone ( estrogensoderzhaschie ointments - ovestin ) glucocorticosteroid ointment , vitamin therapy (vitamins C, E, A, group B ) , procaine blockade pudendal nerve , surgical denervation . With the ineffectiveness of conservative therapy perform surgical excision of affected areas .

When vulvar leukoplakia used destructive methods of treatment ( cryo , elektrodestruktsiya , laser treatment ) .